BDBM307521 2-((4-((2-amino-4-(butylamino)-6-methylpyrimidin-5-yl)methyl)-3-methoxybenzyl) (ethyl)amino)acetic acid::US10150743, Example 2::US10562861, Ex. No. 2
SMILES CCCCNc1nc(N)nc(C)c1Cc1ccc(CN(CC)CC(O)=O)cc1OC
InChI Key InChIKey=ZXPNPUZYBKVZFN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 307521
Affinity DataEC50: 6.10E+3nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the secr...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:TLR8/NF-kB/SEAPorter™ HEK 293 Cell Line (Imgenex Corporation) is a stably co-transfected cell line which expresses full-length human TLR8 and the sec...More data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Recombinant human TLR7 was stably expressed in a HEK293 cell line already stably expressing the pNiFty2-SEAP reporter plasmid; integration of the rep...More data for this Ligand-Target Pair