BDBM310631 US10150762, Example 2/16
SMILES C[C@@H]1CCCN1C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(=O)NCC(C)(C)O
InChI Key InChIKey=ZQHVEGQHOKDZEN-SNVBAGLBSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 310631
Affinity DataIC50: 430nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of GAL4 DNA-binding domain fused full length human RORbeta (201 to 459 residues) expressed in HEK293T cells incubated for 16 to 20 hrs by ...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of GAL4 DNA-binding domain fused full length human RORalpha (305 to 556 residues) expressed in HEK293T cells incubated for 16 to 20 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of GAL4 DNA-binding domain fused full length human RORgammat (1 to 497 residues) expressed in HEK293T cells incubated for 16 to 20 hrs by ...More data for this Ligand-Target Pair