BDBM310886 6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-7-one::US10150767, Example 31::US10150767, Example 33

SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=KQAKWCUGTBVOMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310886   

TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)
Affinity DataIC50:  260nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)
Affinity DataIC50:  170nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent