BDBM311108 N-ethyl-N-(2-(4-(2- hydroxypropan-2-yl)- 5-methyl-2H-1,2,3- triazol-2-yl)ethyl)-3- (pyridin-2- yl)pyrazine-2- carboxamide::US10155750, Example 45

SMILES CCN(CCn1nc(C)c(n1)C(C)(C)O)C(=O)c1nccnc1-c1ccccn1

InChI Key InChIKey=UPBVOSXJYZIJOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311108   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311108(N-ethyl-N-(2-(4-(2- hydroxypropan-2-yl)- 5-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:The cells are seeded at 20,000 cells/well into Becton-Dickinson black 384-well clear bottom sterile plates coated with poly-D-lysine. All reagents we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM311108(N-ethyl-N-(2-(4-(2- hydroxypropan-2-yl)- 5-methyl-...)
Affinity DataIC50:  87nMAssay Description:The cells are seeded at 20,000 cells/well into Becton-Dickinson black 384-well clear bottom sterile plates coated with poly-D-lysine. All reagents we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent