BDBM311193 (S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyridin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine::US10155760, Example 37::US10351563, Example 37::US10544120, Example 37::US10723734, Example 37::US10981910, Example 37::US9902722, Example 37
SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F
InChI Key InChIKey=NGBWQVJCOYTGOR-FQEVSTJZSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 311193
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BFC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of BIKE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of GAK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of CRIK (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of PKG2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of PRK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair