BDBM311287 (S)-1-((2′-chloro-4-(difluoromethyl)-5′-fluoro-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine::US10155760, Example 143::US10351563, Example 143::US10544120, Example 143::US10723734, Example 143::US10981910, Example 143::US9902722, Example 143

SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1cc(Cl)ncc1F

InChI Key InChIKey=SISQPPCZDPNKAD-SFHVURJKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 311287   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311287((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Affinity DataIC50:  0.450nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent