BDBM312238 7-(6-Methylpyridazin-3-yl)-4-p-tolyl-1,2,3,4-tetrahydroquinoline::US9604960, 1

SMILES Cc1ccc(cc1)C1CCNc2cc(ccc12)-c1ccc(C)nn1

InChI Key InChIKey=PNIRPCYOHLVXBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 312238   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM312238(7-(6-Methylpyridazin-3-yl)-4-p-tolyl-1,2,3,4-tetra...)
Affinity DataIC50:  28nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM312238(7-(6-Methylpyridazin-3-yl)-4-p-tolyl-1,2,3,4-tetra...)
Affinity DataIC50:  174nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM312238(7-(6-Methylpyridazin-3-yl)-4-p-tolyl-1,2,3,4-tetra...)
Affinity DataIC50:  65nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent