BDBM31229 isoindolinone scaffold, 15

SMILES OC[C@H](NC1(N(Cc2ccccc2)C(=O)c2ccccc12)c1ccccc1)[C@@H](O)c1ccccc1

InChI Key InChIKey=JAWSNXONTCNKDG-SRBHEWTHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31229   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31229(isoindolinone scaffold, 15)
Affinity DataIC50:  8.50E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed