BDBM31231 CHEMBL360920::isoindolinone scaffold, 17

SMILES CCCN1C(=O)c2ccccc2C1(NC(=O)c1ccccc1)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=MEIUKHKAHGJIIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31231   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31231(CHEMBL360920 | isoindolinone scaffold, 17)
Affinity DataIC50:  6.60E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed