BDBM31240 isoindolinone scaffold, 28

SMILES O=C1N(Cc2ccccc2)C(OCCN2CCNCC2)(c2ccccc12)c1ccccc1

InChI Key InChIKey=XKJRGWIKSJTTGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31240   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31240(isoindolinone scaffold, 28)
Affinity DataIC50:  3.15E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed