BDBM31249 isoindolinone scaffold, 38

SMILES CN(CCOC1(N(Cc2ccccc2)C(=O)c2ccccc12)c1ccccc1)c1ccc(C=O)cc1

InChI Key InChIKey=YQKMCTUAVWARPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31249   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31249(isoindolinone scaffold, 38)
Affinity DataIC50:  1.91E+5nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed