BDBM31251 CHEMBL178106::isoindolinone scaffold, 40

SMILES COc1cc(COC2(N(Cc3ccccc3)C(=O)c3ccccc23)c2ccccc2)cc(OC)c1O

InChI Key InChIKey=MGACPMHHENLBAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31251   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31251(CHEMBL178106 | isoindolinone scaffold, 40)
Affinity DataIC50:  1.79E+4nMpH: 7.4 T: 2°CAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed