BDBM31256 isoindolinone scaffold, 47

SMILES COc1ccc(cc1)[C@@H](O)COC1(N(Cc2ccco2)C(=O)c2ccccc12)c1ccccc1

InChI Key InChIKey=PJTZJMPUXKOJIO-QODXOHEASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31256   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31256(isoindolinone scaffold, 47)
Affinity DataIC50:  1.81E+5nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed