BDBM31258 isoindolinone scaffold, 49

SMILES COC(=O)C(Cc1ccc(O)cc1)N1C(=O)c2ccccc2C1(OCCN(CCC#N)c1ccccc1)c1ccccc1

InChI Key InChIKey=YTCHTPPDEKTOLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31258   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31258(isoindolinone scaffold, 49)
Affinity DataIC50:  8.80E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed