BDBM31268 isoindolinone scaffold, 63

SMILES CCCN1C(=O)c2ccccc2C1(OCc1[nH]cnc1C)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=PNNAWUIWZKMLQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31268   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Newcastle Upon Tyne

LigandPNGBDBM31268(isoindolinone scaffold, 63)
Affinity DataIC50:  6.43E+4nMAssay Description:For initial testing, the compounds and controls were plated out in triplicate into clear 96-well plates (Nunc) in 10 ul aliquots to give final concen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed