BDBM314215 US9611232, Example 7

SMILES NC(=O)CN1[C@@H](c2ccc(F)cc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=XWNOUAOTNUVPPW-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314215   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM314215(US9611232, Example 7)
Affinity DataIC50:  45nMAssay Description:Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent