BDBM315268 1-{1-[5-Methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1H-benzoimidazole::US10172843, Example 3

SMILES Cc1[nH]c(nc1CN1CCC(CC1)n1cnc2ccccc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UBUOXJLXDKQNTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315268   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315268(1-{1-[5-Methyl-2-(4- trifluoromethyl-phenyl)- 1H-i...)
Affinity DataIC50:  450nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent