BDBM315283 6-Bromo-3-[1-[[2-[4- (trifluoromethyl)phenyl]- 1H-imidazol-5- yl]methyl]-4-piperidyl]- 1,4-dihydroquinazolin-2- one::US10172843, Example 17

SMILES FC(F)(F)c1ccc(cc1)-c1ncc(CN2CCC(CC2)N2Cc3cc(Br)ccc3NC2=O)[nH]1

InChI Key InChIKey=CFFZAWVOTPXULD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315283   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315283(6-Bromo-3-[1-[[2-[4- (trifluoromethyl)phenyl]- 1H-...)
Affinity DataIC50:  195nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent