BDBM315295 Acetic acid 2-(6-chloro- 3-{1-[5-methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-2-oxo-2,3-dihydro- benzoimidazol-1-yl)- ethyl ester::US10172843, Example 29

SMILES CC(=O)OCCn1c2cc(Cl)ccc2n(C2CCN(Cc3nc([nH]c3C)-c3ccc(cc3)C(F)(F)F)CC2)c1=O

InChI Key InChIKey=NLJDHPGCOUZYBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315295   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315295(Acetic acid 2-(6-chloro- 3-{1-[5-methyl-2-(4- trif...)
Affinity DataIC50:  280nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent