BDBM315301 5-Chloro-3-(2- methanesulfonyl-ethyl)- 1-{1-[5-methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1,3-dihydro- benzoimidazol-2-one::US10172843, Example 35

SMILES Cc1[nH]c(nc1CN1CCC(CC1)n1c2ccc(Cl)cc2n(CCS(C)(=O)=O)c1=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=LAKAFGDPLZBXQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315301   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315301(5-Chloro-3-(2- methanesulfonyl-ethyl)- 1-{1-[5-met...)
Affinity DataIC50:  257nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent