BDBM315321 3-{1-[5-(2-Methoxy- ethyl)-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3,4-dihydro-1H- quinazolin-2-one::US10172843, Example 55

SMILES COCCc1[nH]c(nc1CN1CCC(CC1)N1Cc2ccccc2NC1=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=QALJAMRXHRTINV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315321   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315321(3-{1-[5-(2-Methoxy- ethyl)-2-(4- trifluoromethyl-p...)
Affinity DataIC50:  350nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent