BDBM315332 3-{1-[1-Methyl-5-(4- trifluoromethyl-phenyl)- 1H-[1,2,4]triazol-3- ylmethyl]-piperidin-4- yl}-3,4-dihydro-1H- quinazolin-2-one::US10172843, Example 66

SMILES Cn1nc(CN2CCC(CC2)N2Cc3ccccc3NC2=O)nc1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BBNFJPUCGCKWEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315332   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315332(3-{1-[1-Methyl-5-(4- trifluoromethyl-phenyl)- 1H-[...)
Affinity DataIC50:  450nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent