BDBM315336 1-{1-[1,5-Dimethyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3-methyl-1,3- dihydro-benzoimidazol- 2-one::US10172843, Example 70

SMILES Cc1c(CN2CCC(CC2)n2c3ccccc3n(C)c2=O)nc(-c2ccc(cc2)C(F)(F)F)n1C

InChI Key InChIKey=CYIRHOADVQKFCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315336   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315336(1-{1-[1,5-Dimethyl-2-(4- trifluoromethyl-phenyl)- ...)
Affinity DataIC50:  245nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent