BDBM315340 3-{1-[2-(4- Methanesulfonyl- phenyl)-5-methyl-1H- imidazol-4-ylmethyl]- piperidin-4-yl}-3,4- dihydro-1H-quinazolin- 2-one::US10172843, Example 74

SMILES Cc1[nH]c(nc1CN1CCC(CC1)N1Cc2ccccc2NC1=O)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FBEMBEAZDUHCQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315340   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315340(3-{1-[2-(4- Methanesulfonyl- phenyl)-5-methyl-1H- ...)
Affinity DataIC50:  94nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent