BDBM315342 3-{1-[1-(2-Methoxy- ethyl)-5-methyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3,4-dihydro-1H- quinazolin-2-one::US10172843, Example 76

SMILES COCCn1c(C)c(CN2CCC(CC2)N2Cc3ccccc3NC2=O)nc1-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=OMMUMJIPKJDCPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315342   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315342(3-{1-[1-(2-Methoxy- ethyl)-5-methyl-2-(4- trifluor...)
Affinity DataIC50:  317nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent