BDBM3160 2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzene)amido]tricyclo[5.2.1.0^{2,6}]decan-8-yl]oxy}carbonyl)phenyl]carbonyl}-3-hydroxybenzoic acid::Balanol analog 26::CHEMBL263910

SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CC(C3CCCC23)[C@H]1NC(=O)c1ccc(O)cc1

InChI Key InChIKey=SSMSJTVEHMWTFZ-IPMVISGLSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 3160   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Protein kinase C zetaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C gamma type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C delta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  970nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C eta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.70E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.20E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alpha isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C eta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C delta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  970nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilon isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C gamma isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C zeta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article