BDBM317457 4-chloro-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquinolin-1(2H)-one::US9623021, 12z

SMILES Oc1ccc(cc1)-n1cc(Cl)c2cc(O)cc(O)c2c1=O

InChI Key InChIKey=OBMYVDPMHJENSJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317457   

TargetEstrogen receptor beta(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM317457(4-chloro-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquino...)
Affinity DataKi:  3nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Gtx

US Patent
LigandPNGBDBM317457(4-chloro-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquino...)
Affinity DataKi:  40nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent