BDBM317465 4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)phenyl)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)-3-methoxy-N- methylbenzamide::US9623028, Compound 79

SMILES CNC(=O)c1ccc(cc1)-c1c[nH]c2nc(Nc3ccc(cc3OC)C(=O)NC)nc(OC3CCCC3)c12

InChI Key InChIKey=YMYOREROCXXANC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317465   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)
Affinity DataIC50:  2.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)
Affinity DataIC50:  34nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)
Affinity DataIC50:  1.91nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(4-(4-(cyclopentyloxy)-5-(4- (methylcarbamoyl)pheny...)
Affinity DataIC50:  58.6nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent