BDBM317629 US10640491, Compound 19::US11104668, Compound 19::US9624201, Compound 19::{5-Amino-1- [4-(2,3- difluoro- phenoxy)-2- methyl- phenyl]-1H- pyrazol-4-yl}- (4-morpholin- 4-ylmethyl- 1H-indol-2-yl)- methanone
SMILES Cc1cc(Oc2cccc(F)c2F)ccc1-n1ncc(C(=O)c2cc3c(CN4CCOCC4)cccc3[nH]2)c1N
InChI Key InChIKey=FUJJFEFRZDEISC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 317629
Affinity DataIC50: 5.59nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 5.59nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 5.59nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair