BDBM317630 3-{4-[5- Amino-4-(4- cyanomethyl- 1H-indole-2- carbonyl)- pyrazol-1-yl]- 3-methyl- phenoxy}- benzonitrile::US10640491, Compound 20::US11104668, Compound 20::US9624201, Compound 20
SMILES Cc1cc(Oc2cccc(c2)C#N)ccc1-n1ncc(C(=O)c2cc3c(CC#N)cccc3[nH]2)c1N
InChI Key InChIKey=IWPIYCRNKUKHCZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 317630
Affinity DataIC50: 8.45nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 8.45nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 8.45nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair