BDBM317640 (R)-5-hydroxy-5-(5-(3-methyl-5-((4-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)thiazol-2-yl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid ::US9624210, Example 1B (R-enantiomer)
SMILES Cc1cc(Nc2nccc(n2)C(F)(F)F)cc(c1)-c1cnc(s1)[C@@]1(O)CCCc2cc(ccc12)C(O)=O
InChI Key InChIKey=HUWSYHXJLSHRDI-RUZDIDTESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317640
Affinity DataIC50: <0.508nMAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair