BDBM3182 2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]azepan-4-yl}oxy)carbonyl]phenyl}carbonyl)-3-hydroxybenzoic acid::Balanol Analog 1(+/-)::CHEMBL49354

SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OC1CCCNCC1NC(=O)c1ccc(O)cc1

InChI Key InChIKey=XYUFCXJZFZPEJD-UHFFFAOYSA-N

Data  16 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 3182   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C zeta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  23nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  38nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C eta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alpha isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C delta isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C gamma isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilon isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Sphinx Laboratories

LigandPNGBDBM3182(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed