BDBM319543 N-[(cyclopropyl- carbamoyl) methyl]-2- methanesulfonyl- 2-(6-phenyl-1,3- benzothiazol- 2-yl)acetamide::US10173991, Example 608
SMILES CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2ccc(cc2s1)-c1ccccc1
InChI Key InChIKey=GHCPCACIMXRWEZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 319543
Affinity DataIC50: 152nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human endothelial lipase derived from human HT1080 cell conditioned media using PED-A1 as substrate incubated for 20 mins and measured ...More data for this Ligand-Target Pair