BDBM31962 carbohydrazide derivative, 5e

SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1Br

InChI Key InChIKey=MCVUTQRJNVPFIL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31962   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM31962(carbohydrazide derivative, 5e)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ(Helicobacter pylori (Campylobacter pylori))
Shanghai Institute of Materia Medica

LigandPNGBDBM31962(carbohydrazide derivative, 5e)
Affinity DataAssay Description:The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed