BDBM320333 (2R)-4-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-3-[4-(2Ha)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-5H-pyrido[3,2-b]indol-8-yl}-2-methyl-1λ6,4-thiomorpholine-1,1-dione::US10174024, Example 51

SMILES C[C@@H]1CN(CCS1(=O)=O)c1ccc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c2c1)-c1c(C)nnn1C

InChI Key InChIKey=KXLKZGBBDBNVAJ-CGKQSPDFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320333   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM320333((2R)-4-{5-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-...)
Affinity DataIC50: <1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent