BDBM321281 N-[3-(benzylmethylamino)propyl]-3-dimethylaminobenzamide::US10179761, Compound 3.1.30

SMILES CN(CCCNC(=O)c1cccc(c1)N(C)C)Cc1ccccc1

InChI Key InChIKey=ZJUIXZLQJIZZJN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 321281   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321281(N-[3-(benzylmethylamino)propyl]-3-dimethylaminoben...)
Affinity DataKi:  1.90nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321281(N-[3-(benzylmethylamino)propyl]-3-dimethylaminoben...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321281(N-[3-(benzylmethylamino)propyl]-3-dimethylaminoben...)
Affinity DataKi:  321nMAssay Description:Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed