BDBM321402 6-[(E)-but-2-enyl]-4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 81
SMILES C\C=C\Cn1cc(-c2ccc(cc2)C(C)(C)O)c2cc[nH]c2c1=O
InChI Key InChIKey=HCKOJNDQXGXWSS-SNAWJCMRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 321402
Affinity DataIC50: 17nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Displacement of biotinylated small-molecule ligand from recombinant His-tagged BRD9 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of biotinylated small-molecule ligand from recombinant His-tagged BRD4 bromodomain 1 (unknown origin) measured after 10 mins by TR-FRET ...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Binding affinity to ZsGreen fused-BRD9 (M1 to T597 residues) (unknown origin) expressed in human U2OS-C433 cells assessed as induction of protein bro...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of biotinylated small-molecule ligand from recombinant His-tagged CECR2 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of biotinylated small-molecule ligand from recombinant His-tagged TAF1 bromodomain 2 (unknown origin) measured after 10 mins by TR-FRET ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Displacement of biotinylated small-molecule ligand from recombinant His-tagged BRD4 bromodomain 2 (unknown origin) measured after 10 mins by TR-FRET ...More data for this Ligand-Target Pair