BDBM321414 6-[(E)-but-2-enyl]-4-[3-chloro-4-(4-methylpiperazine-1-carbonyl)phenyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 99

SMILES C\C=C\Cn1cc(-c2ccc(C(=O)N3CCN(C)CC3)c(Cl)c2)c2cc(C)[nH]c2c1=O

InChI Key InChIKey=SSLCIDPUTUTQRT-SNAWJCMRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321414   

TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM321414(6-[(E)-but-2-enyl]-4-[3-chloro-4-(4-methylpiperazi...)
Affinity DataIC50:  9nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent