BDBM321426 6-but-2-enyl-4-[3-methoxy-5-(4-methylpiperazine-1-carbonyl)-2-pyridyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 110

SMILES COc1cc(cnc1-c1cn(CC=CC)c(=O)c2[nH]c(C)cc12)C(=O)N1CCN(C)CC1

InChI Key InChIKey=ZGGFJUPILNFQTI-AATRIKPKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321426   

TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM321426(6-but-2-enyl-4-[3-methoxy-5-(4-methylpiperazine-1-...)
Affinity DataIC50:  39nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent