BDBM322711 6-(4-((2-cycloheptyl-5-oxo-5,6- dihydropyrimido[4,5-d]pyridazin-4-yl) amino)phenyl)-6-azaspiro[2.5]octane- 1-carboxylic acid::US10183944, Example 81::US10647720, Ex. # 81
SMILES OC(=O)C1CC11CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)C2CCCCCC2)cc1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322711
Affinity DataIC50: <50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair