BDBM32298 (E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-one::(E)-3-[5-(4-methylphenyl)-2-furanyl]-1-phenyl-2-propen-1-one::(E)-3-[5-(4-methylphenyl)furan-2-yl]-1-phenyl-prop-2-en-1-one::(E)-3-[5-(4-methylphenyl)furan-2-yl]-1-phenylprop-2-en-1-one::1-Phenyl-3-(5-p-tolyl-furan-2-yl)-propenone::MLS000567588::SMR000175496::cid_5706152

SMILES Cc1ccc(cc1)-c1ccc(\C=C\C(=O)c2ccccc2)o1

InChI Key InChIKey=WOCJLAHKZCYXRF-ACCUITESSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32298   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32298((E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-on...)
Affinity DataEC50:  5.19E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32298((E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-on...)
Affinity DataEC50:  7.03E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32298((E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-on...)
Affinity DataEC50:  1.32E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32298((E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-on...)
Affinity DataEC50:  8.47E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32298((E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-on...)
Affinity DataEC50:  3.56E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay