BDBM323630 (R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)pyrimidine-5- carboxamido)methyl)phenyl)acetic acid::US10188653, Example 18.2::US9789110, 18.2

SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1cccc(CC(O)=O)c1

InChI Key InChIKey=MQFAVZJCGDDYES-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323630   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323630((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...)
Affinity DataIC50:  156nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323630((R)-2-(3-((2-(3-(2- ethoxyphenoxy)piperidin-1- yl)...)
Affinity DataIC50:  156nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent