BDBM32371 adenosine-derived inhibitor (Grp78), 3::adenosine-derived inhibitor, 5

SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=ISWTXTWJONWIEN-KQYNXXCUSA-N

Data  3 KI  1 IC50  3 Kd  1 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32371   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM32371(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Affinity DataKi:  2.42E+3nMAssay Description:Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock 70 kDa protein 1A(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM32371(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Affinity DataKi:  8.30E+3nM ΔG°:  -6.93kcal/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM32371(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Affinity DataKi:  1.86E+4nMAssay Description:Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed