BDBM32392 carboxamide, 12a

SMILES O=C(Cc1ccccc1)N(CCNCCN(Cc1ccccc1)C(=O)Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=LAEOAKVXHHPUIC-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32392   

TargetRenin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataKi:  5.70E+3nM ΔG°:  -7.15kcal/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataKi:  9.10E+4nM ΔG°:  -5.47kcal/molepH: 4.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin IV(Plasmodium falciparum)
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataKi:  9.80E+4nM ΔG°:  -5.46kcal/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataIC50: >2.50E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1 [22-457](Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataIC50: >2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
Philipps University Marburg

LigandPNGBDBM32392(carboxamide, 12a)
Affinity DataIC50: >2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed