BDBM32480 piperazine amide, 6g

SMILES Clc1cccc(NC(=O)c2ccc[nH]2)c1N1CCN(CC=C)CC1

InChI Key InChIKey=NGHYJTPCQZDPGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32480   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32480(piperazine amide, 6g)
Affinity DataIC50:  4.50E+3nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32480(piperazine amide, 6g)
Affinity DataIC50:  8.90E+3nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed