BDBM325301 US10189841, Compound I-507::US10399980, Compound I-507::US11161848, Compound I-507

SMILES CCn1c2cnc(nc2n(Cc2ccc(cc2)-c2nc(cn2C)C(F)(F)F)c1=O)-c1cccnc1C(C)C

InChI Key InChIKey=YQVLGKWRSLWLPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 325301   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325301(US10189841, Compound I-507 | US10399980, Compound ...)
Affinity DataIC50: <50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325301(US10189841, Compound I-507 | US10399980, Compound ...)
Affinity DataIC50: <50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325301(US10189841, Compound I-507 | US10399980, Compound ...)
Affinity DataIC50: <50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent