BDBM325814 1-(4-phenoxyphenyl)-3- [(3R)-1- propanoylpiperidin-3-yl]- 1H-pyrazolo[3,4- c]pyridin-7-amine::US9637486, Example 2

SMILES CCC(=O)N1CCC[C@H](C1)c1nn(-c2ccc(Oc3ccccc3)cc2)c2c(N)nccc12

InChI Key InChIKey=VWSDAOSFVVFCEE-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325814   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM325814(1-(4-phenoxyphenyl)-3- [(3R)-1- propanoylpiperidin...)
Affinity DataIC50:  2nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent