BDBM326132 US10273223, Compound D-30::US9637472, Compound D-30

SMILES CN(C)CCCN1CCC(CC1)c1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C3CCCC3)c2c1

InChI Key InChIKey=IAENNRVKXUVARL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326132   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM326132(US10273223, Compound D-30 | US9637472, Compound D-...)
Affinity DataIC50: <300nMAssay Description:eneral Procedure for Wild-Type PRC2 Enzyme Assay on Oligonucleosome Substrate. The assays was performed in a buffer consisting of 20 mM bicine (pH=7....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM326132(US10273223, Compound D-30 | US9637472, Compound D-...)
Affinity DataIC50: <300nMAssay Description:Recombinant PRC2 Enzymes. Human PRC2 enzymes were purified as 4-component enzyme complexes co-expressed in Spodoptera frugiperda (sf9) cells using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent