BDBM326327 3-[4-(5-chloropyridin-3- yl)-5-[(trans-4- methylcyclohexyl)methyl]- 7-(pyridin-3-ylmethyl)-5H- pyrrolo[3,2-d]pyrimidin-2- yl]-1,2,4-oxadiazol-5(4H)- one::US9637493, 7.1
SMILES C[C@H]1CC[C@H](Cn2cc(Cc3cccnc3)c3nc(nc(-c4cncc(Cl)c4)c23)-c2noc(=O)[nH]2)CC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 326327
Affinity DataIC50: 52nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM...More data for this Ligand-Target Pair