BDBM327826 (R)-2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)piperazin-1-yl)acetic acid::US9663476, Compound 1::US9663476, Compound 88

SMILES OC(=O)CN1CCN(CC1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=JXBXMYFRUKHWCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327826   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM327826((R)-2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)...)
Affinity DataIC50:  134nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM327826((R)-2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)...)
Affinity DataIC50:  79.1nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
In DepthDetails US Patent